“电工学实验”混合教学模式的探索与实践

在大类培养改革背景下,基于“电工学实验”开放式实践教学体系现状进行了“电工学实验”混合教学模式的研究,建立了“微课”资源并通过新型教学平台进行推送,确立了完备的混合教学模式应用机制并在部分专业进行了试点,通过分析试点调查数据得出混合教学模式具有在实验教学中提高学生学习效率、激发学生学习动力、促进学生个性发展、培养学生实践应用能力的优势,是落实创新应用型人才培养目标的重要举措。     

The social profitability of rural roads in a small open economy: Do urban agglomeration economies matter?

The effects of a rural roads programme depend on labour mobility, how the programme is financed, and agglomeration economies. If financed by a rural poll tax and cross-price effects and agglomeration economies are sufficiently small, the wage will rise, with some return migration. Taxes on trade act as countervailing distortions, yielding urban households some relief. Rural-urban commuting promotes the exploitation of agglomeration economies; taxes on international trade are then inferior to a poll tax. The change in the value, at producer prices, of the rural sector's net supply vector can be a poor measure of the programme's social profitability.     

Influence of high energy ball milling on structural,microstructural and optical properties of TiO2 nanoparticles

The influence of high-energy ball milling on structural, microstructural, and optical properties of TiO₂ by modifying the nanoparticle size was studied. Five samples were extracted at different milling times (0, 2, 4, 8, and 13 h). The average particle sizes estimated by dynamic light scattering (DLS) were 205, 155.8, 116.8, 82.9, and 82.7 nm at 0, 2, 4, 8, and 13 h, respectively. X-ray diffraction analysis confirmed progressive broadening of the peaks as the milling time elapsed. Besides, a correlation was found between d spacing and the average crystal size. The UV–Vis diffuse reflectance spectra of TiO₂ revealed a decrease in reflectance due to particle size reduction. Similarly, an alteration of the bandgap transition energy was presented, whose values gradually decreased from 2.966 eV to 2.861 eV for the sample without and with the maximum duration milling performed (13 h), respectively. Likewise, the SEM analysis showed a distribution in nanoparticle size that became more homogeneous and smaller average grain size as the milling duration was longer.     

水力空化改质对重质原油沥青质及性质的影响

利用水力空化过程产生局部的高温、高压、高射流以及强大的剪切力等极端化学物理条件改质处理沙特重质原油，试验结果表明：沙特重质原油经过水力空化改质后粘度由13.61降低至7.22mm2/s，残碳由7.16%降低至6.48%，实沸点蒸馏后减压渣油降低1个百分点。进一步采用APPI FT-IR MS、XRD、FT-IR、SEM和粒度分布等技术研究了水力空化改质对沙重原油分子组成，沥青质团聚体微晶结构、沥青质胶束粒径分布、沥青质官能团、沥青质形貌等方面的影响，从分子角度阐述空化改质重油的机理。研究结果表明：水力空化改质后沙重原油分子量分布、芳烃类化合物缔合作用变小；沥青质对低DBE化合物吸附性能降低；沥青质团聚体微晶结构更加松散；沥青质胶束粒度分布降低；沥青质分子相互团聚作用力减弱。进一步考察了水力空化改质前后减压渣油延迟焦化性能，改质处理后焦炭产率降低1.85个百分点，液体收率和气体产率分别增加1.52和0.33个百分点，水力空化改质对沥青质性质、结构特点的改善能够有效的提高其加工性能。     

基于VR技术的智能变电站运行仿真培训系统

为了更加真实、直观地呈现智能变电站的运行整体结构,构建基于VR技术的智能变电站运行仿真培训系统。该系统通过5个模块协同完成智能变电站运行仿真培训,结合实际变电站的设备情况,采用二维纹理映射方法完成变电站设备仿真建模;系统利用虚拟现实交互模块呈现培训场景,参与培训人员能够通过人机交互设备,实现场景漫游和相关培训内容操作。测试结果表明:该系统能够较好地模拟出智能变电站的实际运行情况,参与培训的人员可以身临其境地完成整个变电站的巡视,更真实、直观地呈现智能变电站的整体状态。     

Effect of the particle size ratio on macro- and mesoscopic shear characteristics of the geogrid-reinforced rubber and sand mixture interface

As a new type of material for civil engineering projects, the rubber and sand mixture is widely used in roadbed fillers, offering environmental benefits over traditional tyre disposal methods. This study uses a large-scale direct shear apparatus to examine the interface shear properties of the geogrid-reinforced rubber and sand mixture, considering different particle size ratios (r), rubber contents, and normal stresses. Based on indoor tests, direct shear models of the mixture with different values of r are established in PFC^3D, revealing the meso-mechanical mechanism of the mixture in the direct shear process. The results show that when r is greater than 1, incorporating a certain amount of rubber particles can increase the shear strength of the mixture. The r values of 15.78, 7.63, and 3.98 correspond to an optimal rubber content of 30%, 10%, and 20%, respectively. When r is less than 1, mixing rubber particles can only reduce the shear strength of the mixture. When the rubber content is low, the smaller the value of r, the greater is the thickness of the shear band. Furthermore, the normal and tangential contact forces are greater. The fabric anisotropy evolution law of the mixture is consistent with the change in the contact force distribution.     

Structural,optical, cytotoxicity,and antimicrobial properties of MgO,ZnO and MgO/ZnO nanocomposite for biomedical applications

In this study, MgO nanoparticles were successfully fabricated and incubated inside ZnO NPs to form MgO/ZnO nanocomposite for biomedical applications. The x-ray diffraction analysis of MgO, ZnO, and MgO/ZnO has shown the single-phase x-ray diffraction patterns through X'pert High score. The crystallite sizes were calculated as 18 nm, 42 nm, and 53 nm, respectively. The average particle size of MgO, ZnO, and MgO/ZnO nanopowders depicted from secondary electron images of field emission electron microscopy were 56 nm, 400 nm, and 450 nm, respectively. The presence of MgO NPs inside ZnO NPs was confirmed by transmission electron microscopy. The elemental dispersive spectroscopy of MgO, given the peaks of oxygen and magnesium, also showed only zinc and oxygen peaks in ZnO, which confirms no other impurities in MgO and ZnO powders. The elemental analysis of MgO/ZnO nanocomposite showed the peaks of Zinc and Oxygen, along with a tiny peak of Mg. The photoluminescence and UV–vis spectroscopy revealed the absorbance fluorescence limit of the nanomaterials. Fourier transform infrared spectroscopy confirmed the several groups present in the nanocomposite. The biocompatibility of MgO, ZnO, and MgO/ZnO was observed with human peripheral blood mononuclear cells. The cytotoxicity studies were also performed against human cancer (liver and breast) cell lines. The MgO, ZnO, and MgO/ZnO exhibited the antimicrobial properties against Escherichia coli and Staphylococcus aureus.     

Human DDX17 Unwinds Rift Valley Fever Virus Non-Coding RNAs

Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the Bunyaviridae family that causes high rates of mortality and morbidity in humans and ruminant animals. Previous studies indicated that DEAD-box helicase 17 (DDX17) restricts RVFV replication by recognizing two primary non-coding RNAs in the S-segment of the genome: the intergenic region (IGR) and 5′ non-coding region (NCR). However, we lack molecular insights into the direct binding of DDX17 with RVFV non-coding RNAs and information on the unwinding of both non-coding RNAs by DDX17. Therefore, we performed an extensive biophysical analysis of the DDX17 helicase domain (DDX17_135–555) and RVFV non-coding RNAs, IGR and 5’ NCR. The homogeneity studies using analytical ultracentrifugation indicated that DDX17_135–555, IGR, and 5’ NCR are pure. Next, we performed small-angle X-ray scattering (SAXS) experiments, which suggested that DDX17 and both RNAs are homogenous as well. SAXS analysis also demonstrated that DDX17 is globular to an extent, whereas the RNAs adopt an extended conformation in solution. Subsequently, microscale thermophoresis (MST) experiments were performed to investigate the direct binding of DDX17 to the non-coding RNAs. The MST experiments demonstrated that DDX17 binds with the IGR and 5’ NCR with a dissociation constant of 5.77 ± 0.15 µM and 9.85 ± 0.11 µM, respectively. As DDX17_135–555 is an RNA helicase, we next determined if it could unwind IGR and NCR. We developed a helicase assay using MST and fluorescently-labeled oligos, which suggested DDX17_135–555 can unwind both RNAs. Overall, our study provides direct evidence of DDX17_135–555 interacting with and unwinding RVFV non-coding regions.